Defining Essential Genes and Targetable Vulnerabilities in Infant Pineoblastoma

Award: $105,000 over 1 year (2022-2023)
Principal Investigators: Dr. Annie Huang, Sick Kids of Toronto
Funding Partners: Blake Vince Payne Star Fund

This project combines CRISPRi technology with a Zebra Fish brain tumor model to uncover key druggable pathways for RB1/MYC driven infant Pineoblastoma.