Advancing Research

The largest patient advocacy funder of pediatric brain tumor research, the Pediatric Brain Tumor Foundation is wholly dedicated to ending the most commonly diagnosed and deadliest childhood cancer.

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PLGA Research

The Pediatric Brain Tumor Foundation's PLGA research investments accelerate the pace of scientific discovery and drug development for children with low-grade gliomas and astrocytomas.


Pediatric low-grade gliomas (PLGG) are the most common type of brain tumor diagnosed in children. Although these tumors grow more slowly than high-grade brain tumors, about half of PLGG patients who undergo surgery will relapse and require additional treatments.

The Pediatric Brain Tumor Foundation supports research dedicated to pediatric low-grade gliomas and astrocytomas (the most common type of PLGG). Over the past decade, our funding and strategic leadership have helped:

  • secure multi-million-dollar grants from the National Cancer Institute to super-charge research efforts
  • improve doctors’ understanding of what causes pediatric low-grade gliomas and makes some types more aggressive than others
  • discover and develop multiple treatments being used in clinics today

We also fund and advocate for PLGG survivorship research to improve patients’ long-term survival and quality of life.

The research we fund would not exist without your generosity. Donate or start a fundraiser today to support the next generation of scientific discovery.

Support for PLGG Families

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PLGG/PLGA Facebook Group

PLGG/PLGA Facebook Group

In this Facebook group, you can ask questions, share your experiences, and find support from other families impacted by pediatric low-grade gliomas and astrocytomas.

Video: PLGG Types & Treatments

Video: PLGG Types & Treatments

Learn about common pediatric low-grade glioma types and treatments in this on-demand webinar featuring Dr. Tab Cooney, Medical Director of Day One Biopharmaceuticals.

For Researchers
Caucasian Scientists use microscopes to research the covid-19 virus vaccine in a medical laboratory. Doctor uses biotechnology to research coronavirus in chemistry lab. Pharmaceutical science.

For Researchers

The PBTF awards grants for research on an ongoing basis. Learn how to apply for funding.