Molecular JPA Study

This study by Dr. KK Wong at MD Anderson Cancer Center 1) analyzes the gene expression profiles in 40-60 cases of subtotally resected JPAs located at the midline region to test whether midline located JPA also forms two subgroups with one group more aggressive, and (2) identifies prognostic markers that can predict the likelihood of progression in subtotally resected JPAs using statistical methods. Dr. Wong submitted his study to the NIH and was granted funding; however, the funding was not sufficient to cover the entire sample size. This would have required Dr. Wong to decrease his sample size, thus jeopardizing the significance of the results. The incremental funding necessary to keep the study intact was funded by funds raised by families for the Childhood Brain Tumor Foundation, who conducted a special peer review to confirm the viability of the study. The PLGA Foundation recognizes the Childhood Brain Tumor Foundation for their support of this program.

Funded in 2007.

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